Àá½Ã¸¸ ±â´Ù·Á ÁÖ¼¼¿ä. ·ÎµùÁßÀÔ´Ï´Ù.

¹æ»ç¼±Á¶»ç°¡ ÇϾǰúµÎ¿¡ ¹ÌÄ¡´Â ¿µÇâ¿¡ °üÇÑ ÀüÀÚÇö¹Ì°æÀû ¿¬±¸

ELECTRON MICROSCOPIC STUDY OF THE IRRADIATION EFFECT ON THE RAT MANDIBULAR CONDYLE

Ä¡°ú¹æ»ç¼± 1996³â 26±Ç 2È£ p.45 ~ 63
¹Ú¸í¼±, ±è¼ö¿ë,
¼Ò¼Ó »ó¼¼Á¤º¸
¹Ú¸í¼± (  ) - ¼­¿ï´ëÇб³ Ä¡°ú´ëÇÐ ±¸°­¾Ç¾È¸é¹æ»ç¼±Çб³½Ç
±è¼ö¿ë (  ) - ¼­¿ï´ëÇб³ Ä¡°ú´ëÇÐ ±¸°­¾Ç¾È¸é¹æ»ç¼±ÇÐ

Abstract

¹æ»ç¼±Á¶»ç°¡ ÇϾǰúµÎ¼ºÀå¿¡ ¹ÌÄ¡´Â ¿µÇâ¿¡ ´ëÇÏ¿© ¿¬±¸ÇÏ°íÀÚ »ýÈÄ 20ÀÏµÈ ¾ÏÄƹ鼭
(Sprague-Dawley) 27¸¶¸®¸¦ ¼¼±ºÀ¸·Î ³ª´©¾î ¼¼½·-137À» ¼±¿øÀ¸·Î »ç¿ëÇÏ´Â MK Cell
Irra-diator·Î 5 Gy, 10 Gy, 20 GyÀÇ ¹æ»ç¼±À» ¿ìÃø¿¡¼­ Àü½ÅÁ¶»çÇÏ¿´À¸¸ç Á¶»çÈÄ 1, 7. 14
ÀÏ µÇ´Â ³¯¿¡ 3¸¶¸®¾¿ Èñ»ýÇÑ ÈÄ ±¤ÇÐÇö¹Ì°æ°ú ÀüÀÚÇö¹Ì°æÀ¸·Î °üÂûÇÏ¿© ´ÙÀ½°ú °°Àº °á·Ð
À» ¾ò¾ú´Ù.
1. Áõ½Ä´ë¿¡¼­´Â 5 Gy Á¶»ç½Ã ¼¼Æ÷¼Ò±â°üÀÌ Æı«µÈ ¼¼Æ÷°¡ ÀϺΠ°üÂûµÇ¾úÀ¸¸ç 10 Gy Á¶
»ç½Ã´Â ¼¼Æ÷¼Ò±â°üÀÌ Æı«µÈ ¼¼Æ÷¼öÀÇ Áõ°¡¿Í ÇÔ²² »ç¸³Ã¼ÀÇ È®ÀåÀÌ ´ëºÎºÐÀÇ ¼¼Æ÷¿¡¼­ °ü
Âû ¾ú´Ù. ¶Ç, 20 Gy Á¶»ç½Ã ¿¡´Â À§ÀÇ º¯È­¿Í ÇÔ²² ¼¼Æ÷¼ö°¡ ±Þ°ÝÈ÷ °¨¼ÒÇÏ¿´´Ù.
2. ºñ´ë´ë¿¡¼­´Â 5 Gy Á¶»ç½Ã ºÒ±ÔÄ¢ÇÑ ºñ´ë¾ç»ó°ú ¾à°£ÀÇ ÆøÀÇ °¨¼Ò°¡ °üÂûµÇ¾úÀ¸¸ç
l0Gy¿Í 20 Gy Á¶»ç½Ã¿¡´Â ÀÌ·¯ÇÑ º¯È­°¡ ´õ¿í ½ÉÇÏ¿´´Ù.
3. »óºÎºñ´ë´ë¿¡¼­ ÀϺΠ¿¬°ñ¼¼Æ÷ÀÇ ±«»ç°¡ ¸ðµç ½ÇÇ豺¿¡¼­ °üÂûµÇ¾úÀ¸¸ç ¿¬°ñ¼¼Æ÷³» ÇÙ
ÀÇ ±Ø¼ºÀÌ 10 Gy, 20 GyÁ¶»ç±º¿¡¼­´Â °ÅÀÇ °üÂûµÇÁö ¾Ê°Å³ª ±× Á¤µµ°¡ ¹Ì¾àÇÏ¿´´Ù.
4. 5 Gy, 10 Gy, 20 Gy Á¶»ç±º ¸ðµÎ¿¡¼­ Á¶»çÈÄ 7ÀÏ¿¡¼­ Á¶Á÷ÇÐÀû º¯È­°¡ °¡Àå ½ÉÇÏ¿´°í
Á¶»ç ÈÄ 14ÀÏ¿¡¼­´Â ȸº¹ ¼Ò°ßÀÌ °üÂûµÇ¾ú´Ù.
#ÃÊ·Ï#
In attempt to determine radiation effect on the mandibular condyle of the growing rat,
27 white female rats (Sprague-Dawley) were divided into 3 groups and irradiated
respectively 5 Gy, 10 Gy,20 Gy using MK Cell Irradiator. Mandibular condyles from rats
on the day of 1, 7, 14 after the irradiation day were obtained, sectioned sagittally and
examined by light microscopy, and thereafter middle portion through anteroposterior
direction on the sagittal plane was selected to examine the ultrastructural change by
transmission electron microscopy.
The obtained results are followings.
1. In the proliferative zone some cells showed little organelles in case of 5 Gy
irradiation, in addition the number of degenerative cells increased and in case of 10 Gy
irradiation, and in case of 20 Gy irradiation total number of cells decreased.
2. In the hypertrophic zone, narrowing of width and partial disorder in hypertrophic
process were noted in case of both irradiation, and more prominent narrowing of width
and more irregular disorder in hypetrophic process in Case of both 10 Gy and 20 Gy
irradiation.
3. In the upper hypertrophic zone some chondrocytes seemed to be dying and the
polarity of nuclei could not be seen, if any.
4. The periodic observation showed the severest change at day 7 and the signs of
recovery at day 14 after irradiation.

Å°¿öµå

Irradiation; Mandibular condyle; Transmission Electron Microscopy;

¿ø¹® ¹× ¸µÅ©¾Æ¿ô Á¤º¸

  

µîÀçÀú³Î Á¤º¸